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Claudio Brancolini Selected Research

2,3-dimethoxy-1,4-naphthoquinone

1/2020GSK3β is a key regulator of the ROS-dependent necrotic death induced by the quinone DMNQ.
9/2014A receptor-interacting protein 1 (RIP1)-independent necrotic death under the control of protein phosphatase PP2A that involves the reorganization of actin cytoskeleton and the action of cofilin-1.

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Claudio Brancolini Research Topics

Disease

14Neoplasms (Cancer)
01/2019 - 10/2003
5Necrosis
01/2020 - 03/2009
3Glioblastoma (Glioblastoma Multiforme)
02/2015 - 11/2009
2Leiomyosarcoma
01/2022 - 01/2020
2Carcinogenesis
12/2005 - 06/2005
1Neuroendocrine Tumors (Neuroendocrine Tumor)
01/2021
1Lung Neoplasms (Lung Cancer)
01/2021
1Neuroblastoma
12/2016
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
07/2016
1Leukemia
07/2016
1Virus Diseases (Viral Diseases)
12/2012
1Multiple Myeloma
01/2008
1Colonic Neoplasms (Colon Cancer)
06/2005
1Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
06/2005
1Peripheral Nervous System Diseases (PNS Diseases)
03/2003
1Mitochondrial Diseases (Mitochondrial Disease)
04/2002

Drug/Important Bio-Agent (IBA)

5Proteasome Endopeptidase Complex (Proteasome)IBA
07/2016 - 06/2005
4UbiquitinIBA
07/2016 - 12/2005
4Bortezomib (Velcade)FDA Link
07/2016 - 12/2005
3Proteins (Proteins, Gene)FDA Link
01/2019 - 06/2005
3CaspasesIBA
01/2011 - 09/2006
2Histone Deacetylases (Histone Deacetylase)IBA
01/2022 - 01/2021
2Glutathione (Reduced Glutathione)IBA
01/2020 - 11/2009
2AntioxidantsIBA
01/2020 - 03/2009
22,3-dimethoxy-1,4-naphthoquinoneIBA
01/2020 - 09/2014
2isopeptidaseIBA
07/2016 - 02/2015
2HMGB1 Protein (HMG1)IBA
09/2014 - 03/2009
2Caspase 2IBA
01/2014 - 04/2002
1Transcription Factors (Transcription Factor)IBA
01/2022
1Interleukin-10 (Interleukin 10)IBA
01/2021
1Death Domain ReceptorsIBA
01/2020
1NRH - quinone oxidoreductase2IBA
01/2020
1NAD (NADH)IBA
01/2020
1Oxidoreductases (Dehydrogenase)IBA
01/2020
1quinone (benzoquinone)IBA
01/2020
1Phenobarbital (Luminal)FDA Link
01/2019
1MEF2 Transcription FactorsIBA
12/2018
1Co-Repressor ProteinsIBA
01/2017
1Histones (Histone)IBA
12/2016
1IminesIBA
12/2016
1Deubiquitinating EnzymesIBA
02/2015
1Reactive Oxygen Species (Oxygen Radicals)IBA
09/2014
1Actin Depolymerizing Factors (Cofilins)IBA
09/2014
1CholesterolIBA
01/2014
1TNF-Related Apoptosis-Inducing LigandIBA
12/2013
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2013
1CytokinesIBA
12/2012
1Pharmaceutical PreparationsIBA
01/2010
11,2- bis(2- aminophenoxy)ethane- N,N,N',N'- tetraacetic acid (BAPTA)IBA
03/2009
1Chelating AgentsIBA
03/2009
1EstersIBA
03/2009
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
03/2009
1Small Molecule LibrariesIBA
09/2006
1Proteasome InhibitorsIBA
12/2005
1ElementsIBA
06/2005
1Biological ProductsIBA
06/2005
1Glycogen Synthase KinasesIBA
06/2005
1beta CateninIBA
06/2005
1Histone Deacetylase InhibitorsIBA
10/2003
1Myelin ProteinsIBA
03/2003

Therapy/Procedure

5Therapeutics
01/2021 - 10/2003
1Aftercare (After-Treatment)
07/2016
1Drug Therapy (Chemotherapy)
12/2012